Discovery of a potent nanoparticle P‐selectin antagonist with anti‐inflammatory effects in allergic airway disease
Open Access
- 2 October 2003
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 17 (15) , 2296-2298
- https://doi.org/10.1096/fj.03-0166fje
Abstract
The severity of allergic asthma is dependent, in part, on the intensity of peribronchial inflammation. P‐selectin is known to play a role in the development of allergen‐induced peribronchial inflamma...Keywords
This publication has 57 references indexed in Scilit:
- Glycosulfopeptides modeled on P‐selectin glycoprotein ligand‐1 inhibit P‐selectin‐dependent leukocyte rolling in vivoThe FASEB Journal, 2002
- Synergistic interactions of the two classes of ligand, sialyl‐Lewisa/x fuco‐oligosaccharides and short sulpho‐motifs, with the P‐ and L‐selectins: implications for therapeutic inhibitor designsImmunology, 2002
- A Solid-Phase Synthesis for β-Turn Mimetics of Sialyl Lewis XBioorganic & Medicinal Chemistry Letters, 2000
- Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate-Mediated Biological RecognitionAngewandte Chemie International Edition in English, 1999
- Differing Patterns of P-Selectin Expression in Lung InjuryThe American Journal of Pathology, 1998
- Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC)European Respiratory Journal, 1998
- Synthetic studies on sialoglycoconjugares. Part CVII. Synthetic Studies on Selectin Ligands/Inhibitors. Synthesis and Biological Evaluation of Sulfated and Phosphorylated .BETA.-D-Galacto- and Lactopyranosides Containing Fatty-Alkyl Residues of Different Carbon Chain Lengths.CHEMICAL & PHARMACEUTICAL BULLETIN, 1998
- Severity of Childhood Asthma by Socioeconomic StatusInternational Journal of Epidemiology, 1996
- Role of CD11/CD18 in shear rate-dependent leukocyte-endothelial cell interactions in cat mesenteric venules.Journal of Clinical Investigation, 1991
- Molecular Architecture and Function of Polymeric Oriented Systems: Models for the Study of Organization, Surface Recognition, and Dynamics of BiomembranesAngewandte Chemie International Edition in English, 1988