Active esters and resins in peptide synthesis: the role of steric hindrance
- 1 January 1969
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 21,p. 1259-1260
- https://doi.org/10.1039/c29690001259
Abstract
In solid-phase peptide synthesis, because of the steric hindrance caused by the polymeric support the choice of activating groups should be directed by experiments carried out on the resin and not by the relative reactivities measured in solution.Keywords
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