The relationship between chromatid interference and the mapping function
- 1 January 1976
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 17 (4) , 212-220
- https://doi.org/10.1159/000130714
Abstract
A formula for a general mapping function involving only the number of chiasmata between two points on the chromosome and the average excess of four-stranded double exchanges over two-stranded double exchanges is derived. A formula is also given for deriving the proportion of three-stranded double exchanges after any given number of chiasmata; this is related to mapping for linkage with the centromere. It is shown that this proportion tends to a limit of 2/3 after a large number of chiasmata, whether or not chromatid interference is operating.Keywords
This publication has 2 references indexed in Scilit:
- Estimating distances from the centromere by means of benign ovarian teratomas in manAnnals of Human Genetics, 1976
- A mapping function for human chromosomesAnnals of Human Genetics, 1976