Enantioselective radical-mediated reduction of α-iodolactone using tributyltin hydride in the presence of a chiral amine and a Lewis acid
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 4,p. 481-482
- https://doi.org/10.1039/c39950000481
Abstract
Enantioselective radical-mediated reduction of α-methoxymethyl-α-iododihydrocoumarin 1 using tributyltin hydride is realized in up to 62% enantiomeric excess (e.e.)(88% chemical yield) by combination of chiral diamine 2 and magnesium iodide.Keywords
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