Conformation of Lariat Structures Formed in the Splicing of Pre-mRNA by NMR Spectroscopy
- 1 October 1988
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 7 (5-6) , 827-830
- https://doi.org/10.1080/07328318808056338
Abstract
Temperature dependent 1H- and 31p-NMR studies have shown that lariat (branched) trimers show a preferential 2′ → 5′ stacking, while the branched tetramers resemble 3′ → 5′ linked linear trimers, reminiscent of a single stranded A-RNA helix.Keywords
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