Hodgkin's disease and Epstein-Barr virus
- 1 September 1992
- journal article
- review article
- Published by Elsevier in Annals of Oncology
- Vol. 3 (suppl_4) , S27-S30
- https://doi.org/10.1093/annonc/3.suppl_4.s27
Abstract
Seroepidemiological and molecular biological studies have established an association of Hodgkin's disease with Epstein-Barr virus (EBV). Recently, EBV genomes and gene products, most notably the latent membrane protein (LMP), have been detected in approximately 50% of the cases. The findings suggest that EBV may contribute to the pathoetiology of a sizable proportion of Hodgkin's disease cases.Keywords
This publication has 14 references indexed in Scilit:
- Viral involvement in Hodgkin's disease: detection of clonal type A Epstein-Barr virus genomes in tumour samplesBritish Journal of Cancer, 1991
- Frequent detection of Epstein-Barr virus DNA by the polymerase chain reaction in lymph node biopsies from patients with Hodgkin's disease without genomic evidence of B- or T-cell clonalityBlood, 1991
- Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells.Proceedings of the National Academy of Sciences, 1991
- Detection of Epstein-Barr virus messenger RNA in Reed-Sternberg cells of Hodgkin's disease by in situ hybridization with biotinylated probes on specially processed modified acetone methyl benzoate xylene (ModAMeX) sections [see comments]Blood, 1991
- Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's diseaseThe Lancet, 1991
- Detection of ebv gene expression in reed‐sternberg cells of Hodgkin's diseaseInternational Journal of Cancer, 1990
- High frequency of Epstein‐Barr virus genome detection in Hodgkin's disease of HIV‐positive patientsInternational Journal of Cancer, 1990
- Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1- positive anaplastic large cell lymphoma by combined Southern blot and in situ hybridization [see comments]Blood, 1989
- Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's DiseaseNew England Journal of Medicine, 1989
- Immunoglobulin and T-cell receptor gene rearrangements in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma: Dissociation between phenotype and genotypeLeukemia Research, 1989