Age-associated Decrease of Oxidative Repair Enzymes, Human 8-Oxoguanine DNA Glycosylases (hOgg1), in Human Aging
Open Access
- 1 January 2003
- journal article
- Published by Oxford University Press (OUP) in Journal of Radiation Research
- Vol. 44 (1) , 31-35
- https://doi.org/10.1269/jrr.44.31
Abstract
8-Oxoguanine has been shown to be a dominant cause of oxidative DNA damage by oxygen free radicals in eukaryotic cells. The 8-oxoguanine repair-speciKeywords
This publication has 18 references indexed in Scilit:
- Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient miceCarcinogenesis: Integrative Cancer Research, 2001
- Accumulation of oxidative DNA damage, 8-oxo-2′-deoxyguanosine, and change of repair systems during in vitro cellular aging of cultured human skin fibroblastsMutation Research/DNA Repair, 2001
- The Type of DNA Glycosylase Determines the Base Excision Repair Pathway in Mammalian CellsJournal of Biological Chemistry, 1999
- 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificityMutation Research/DNA Repair, 1997
- Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylaseProceedings of the National Academy of Sciences, 1997
- DNA glycosylases in the base excision repair of DNABiochemical Journal, 1997
- DNA excision repair pathwaysCurrent Opinion in Genetics & Development, 1997
- Oxidative DNA damage and senescence of human diploid fibroblast cells.Proceedings of the National Academy of Sciences, 1995
- Mutagenesis by 8-oxoguanine: an enemy withinTrends in Genetics, 1993
- Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodGNature, 1991