Deoxyribonuclease Inhibitors Produced by Streptomycetes
- 1 January 1993
- journal article
- research article
- Published by Taylor & Francis in Journal of Enzyme Inhibition
- Vol. 7 (1) , 27-32
- https://doi.org/10.3109/14756369309020185
Abstract
Streptomyces sp. strain No. A-5838 produces three types of inhibitors of DNase II. Two of them, DNI-2 and DNI-3, were distinguished from the previously reported DNase II inhibitors, 5838-DNI and 5923-DNI, by their inhibitory profiles towards phosphodiesterases. DNI-2 has Mr 654, and is considered to be a coproporphyrin. DNI-3 is an acidic substance with Mr about 60,000 as estimated by gel filtration. The inhibitory activities of both inhibitors were shown to be temperature-dependent whereas only that of DNI-2 was pH-dependent.Keywords
This publication has 15 references indexed in Scilit:
- THE COLORIMETRIC DETERMINATION OF PHOSPHORUSPublished by Elsevier ,2021
- 5838-DNI, A Deoxyribonuclease Inhibitor Produced byStreptomycesSp. Strain No. A-5838Journal of Enzyme Inhibition, 1992
- 5923-DNI, a New Deoxyribonuclease Inhibitor Produced byStreptomycesSp. Strain No. A-5923Journal of Enzyme Inhibition, 1991
- Mode of Action of Nuclease P1on Nucleic Acids and Its Specificity for Synthetic PhosphodiestersAgricultural and Biological Chemistry, 1974
- Estimation of the double-helical content in various single-stranded nucleic acids by treatment with a single strand-specific nucleaseBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
- 24 Bovine Pancreatic RibonucleasePublished by Elsevier ,1971
- An improved colorimetric determination of amino acids with the use of ninhydrinAnalytical Biochemistry, 1966
- [29] PhosphodiesterasesPublished by Elsevier ,1963
- Studies on calf-intestinal alkaline phosphatase I. Chromatographic purification, microheterogeneity and some other properties of the purified enzymeBiochimica et Biophysica Acta, 1961
- Studies on PolynucleotidesJournal of Biological Chemistry, 1961