Serum Sodium Concentration of Hypertensive Rats: Relation to NaCl Intake, Blood Pressure and Age.

Abstract
Encapsulat-ing both kidneys of young rats (50 - 90 days) in molded latex envelopes produced hypertension and elevated their mean serum Na concentration slightly (2 meq / 1) but significantly above that of control rats. The same procedure in older rats (126 -165 days) produced similar hypertension but mean serum Na concentration remained within normal limits. Elevation of serum Na concentration in younger hypertensive rats was not closely related either to blood pressure level or to volume of 0.15 [image] NaCl solution ingested.

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