Redistribution of histones during unfolding of chromosomal DNA
- 1 October 1973
- journal article
- Published by Springer Nature in Molecular Biology Reports
- Vol. 1 (3) , 143-148
- https://doi.org/10.1007/bf00357154
Abstract
Just in the course of unfolding of chromosomal deoxyribonucleoproteins performed in the absence of magnesium ions all DNA-bound histones may be redistributed. This type of redistribution is completely blocked in already ‘unfolded’ DNP preparations. If the unfolding-induced histone redistribution is allowed it leads to a significant decrease of the average length of free DNA segments in the unfolded, histone F1-depleted DNP. The implications of these data on the mode of DNA packing in chromatin are discussed.Keywords
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