Controlled Release of Insulin from Injectable Biodegradable Triblock Copolymer Depot in ZDF Rats
- 1 December 2003
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 20 (12) , 2008-2010
- https://doi.org/10.1023/b:pham.0000008050.99985.5c
Abstract
Purpose. The purpose of this study was to design sustained release system which provides basal insulin release over a week by one injection in diabetic animals. For an effective injectable...Keywords
This publication has 9 references indexed in Scilit:
- A novel sustained-release formulation of insulin with dramatic reduction in initial rapid releaseJournal of Controlled Release, 2002
- Biodegradable block copolymers for delivery of proteins and water-insoluble drugsJournal of Controlled Release, 2001
- Controlled Release of Insulin from Injectable Biodegradable Triblock CopolymerPharmaceutical Research, 2001
- Diabetes trends in the U.S.: 1990-1998.Diabetes Care, 2000
- Intranasal insulin delivery and therapyAdvanced Drug Delivery Reviews, 1999
- Biodegradable block copolymers as injectable drug-delivery systemsNature, 1997
- The rising global burden of diabetes and its complications: estimates and projections to the year 2010.1997
- Insulin Controlled-Release Microcapsules to Prolong the Hypoglycemic Effect in Diabetic RatsBiomaterials, Artificial Cells and Artificial Organs, 1988
- Long-acting Insulin: Slow Release of Insulin from a Biodegradable Matrix Implanted in Diabetic RatsDiabetes, 1983