Beta2-Microglobulin and Immunodeficiency in a Homosexual Man
- 25 November 1982
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 307 (22) , 1402-1403
- https://doi.org/10.1056/nejm198211253072214
Abstract
To the Editor: Beta2-microglobulin forms the light chain of the HLA antigen on the surface of nucleated cells.1 The turnover of the cell membrane is the main source of the serum beta2-microglobulin, which is then excreted by the kidneys. The serum concentration increases when the glomerular filtration decreases or when the production of beta2-microglobulin increases, as in lymphoproliferative disorders.1 We recently observed a case of immunodeficiency in a homosexual man who had the highest serum level of beta2-microglobulin recorded in our laboratory. The patient was a Swiss citizen residing in New . . .Keywords
This publication has 2 references indexed in Scilit:
- Pneumocystis cariniiPneumonia and Mucosal Candidiasis in Previously Healthy Homosexual MenNew England Journal of Medicine, 1981
- Beta 2-microglobulin in haematological malignancies.BMJ, 1981