Cytochrome P450: Molecular Architecture, Mechanism, and Prospects for Rational Inhibitor Design
- 1 January 1988
- journal article
- review article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 05 (2) , 67-75
- https://doi.org/10.1023/a:1015920931701
Abstract
Cytochromes P450 catalyze the insertion of one O2-derived oxygen atom into an aliphatic or aromatic molecule. P450s are best known for the metabolism of xenobiotic molecules, where hydroxylation...Keywords
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