Nocardicin A, a new monocyclic .BETA.-lactam antibiotic. IV. Factors influencing the in vitro activity of nocardicin A.
- 1 January 1977
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 30 (11) , 926-931
- https://doi.org/10.7164/antibiotics.30.926
Abstract
Factors influencing the in vitro antimicrobial activity of nocardicin A against Pseudomonas aeruginosa and Proteus mirabilis were investigated. Sodium chloride was identified as a major inhibitor. Some of the amino acids, sugars and divalent cations were found to be minor inhibitors. The presence of potassium phosphates enhanced nocardicin A activity against P. aeruginosa, but antagonized the activity against P. mirabilis.Keywords
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