Twelve-hour liver preservation in the pig using hypothermia and hyperbaric oxygen

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Abstract
In an attempt to prolong successful storage of the pig liver beyond the 6–8 hours previously described from this laboratory, the addition of cell-membranestabilizing drugs to the preserving solution and the use of a potassium-rich solution were investigated. Using simple hypothermia alone, 10- and 12-hour storage was unsuccessful. Using the previously described hypothermic technique, but with the addition of hyperbaric oxygen at 3 atmospheres absolute (A.T.A.), consistently successful 12-hour preservation was achieved.
Funding Information
  • the Medical Research Council
  • The C. L. Herman Bequest
  • The Cape Provincial Administration