Distribution of .BETA.-lactam and .BETA.-lactone producing bacteria in nature.
- 1 January 1982
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 35 (7) , 814-821
- https://doi.org/10.7164/antibiotics.35.814
Abstract
Over one million bacteria were isolated from a large variety of soil, plant and water samples collected from different environments and examined in an extremely sensitive and highly specific screen for .beta.-lactam production. A group of 7 related monocyclic .beta.-lactams (monobactams) were isolated from strains representing 4 genera, Agrobacterium, Chromobacterium, Gluconobacter and Pseudomonas. Monobactam-producing strains of Agrobacterium and Pseudomonas were isolated only rarely. Producing strains of Chromobacterium were isolated from a relatively limited number of habitats, while the Gluconobacter strains appeared to be widespread in nature. Three closely related .beta.-lactone-containing molecules were isolated from strains representing 3 genera, Arthrobacter, Bacillus and Pseudomonas. The Bacillus and Pseudomonas strains were isolated infrequently but from a variety of samples. The producing strain of Arthrobacter was isolated only once.This publication has 10 references indexed in Scilit:
- EM5400, a family of monobactam antibiotics produced by Agrobacterium radiobacter. I. Taxonomy, fermentation and biological properties.The Journal of Antibiotics, 1982
- SQ 26,180, a novel monobactam. II. Isolation, structure determination and synthesis.The Journal of Antibiotics, 1982
- Monocyclic β-lactam antibiotics produced by bacteriaNature, 1981
- Sulfazecin and isosulfazecin, novel β-lactam antibiotics of bacterial originNature, 1981
- Sulfazecin,a novel .BETA.-lactam antibiotic of bacterial origin. Isolation and chemical characterization.The Journal of Antibiotics, 1981
- Structure and absolute configuration of thienamycinJournal of the American Chemical Society, 1978
- PS-5, A new .BETA.-lactam antibiotic from Streptomyces.The Journal of Antibiotics, 1977
- Structures of olivanic acid derivatives MM 4550 and MM 13902; two new, fused β-lactams isolated from Streptomyces olivaceusJournal of the Chemical Society, Chemical Communications, 1977
- Nocardicin a, a new monocyclic .BETA.-lactam antibiotic. I. Discovery, isolation and characterization.The Journal of Antibiotics, 1976
- 2 SIMPLE MEDIA FOR THE DEMONSTRATION OF PYOCYANIN AND FLUORESCIN1954