A Cellular Striptease Act
- 13 November 1998
- journal article
- perspective
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 282 (5392) , 1279-1280
- https://doi.org/10.1126/science.282.5392.1279
Abstract
Proteins on the cell surface can be cleaved by proteolytic enzymes. In the Perspective, Werb and Yan outline the many purposes of these cleavage events-to provide ligand for binding to receptors (as shown in the report by Peschon et al. on p. 1281), to eliminate ligand on receptors and to increase or decrease cell-cell interactions. Such proteolysis can be regulated and is turning out to be widely used by the cell.Keywords
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