Synthesis and biological evaluation of radiolabeled .beta.-ruthenocenylalanine
- 1 June 1984
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 27 (6) , 803-806
- https://doi.org/10.1021/jm00372a018
Abstract
Carrier-free beta-[103,106Ru] ruthenocenylalanine was prepared from 103, 106RuCl3 by utilizing ( ruthenocenylmethyl )trimethylammonium iodide as the key synthetic intermediate. The amino acid analogue was evaluated as a pancreatic imaging agent, but no selective uptake in the pancreas was observed in either rats or mice.Keywords
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