In vitro stimulation of primate hemoglobin synthesis by L-thyroxine
Open Access
- 1 March 1977
- journal article
- Published by American Society of Hematology in Blood
- Vol. 49 (3) , 407-413
- https://doi.org/10.1182/blood.v49.3.407.407
Abstract
Bone marrow cells from adult and abortus primates (marmosets) were incubated in vitro to determine their responsiveness to L-thyroxine. 3H- leucine incorporation into purified globin chains was the parameter assayed to determine responsiveness. Bone marrow from spontaneously aborted animals consistently was stimulated by the presence of physiologic levels of L-thyroxine. Bone marrow cells from adult animals were unaffected by the hormone.Keywords
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