Metabolism of Homoorientin by Human Intestinal Bacteria
- 1 September 1988
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 51 (5) , 874-878
- https://doi.org/10.1021/np50059a010
Abstract
As a part of our studies on the metabolism of bioactive compounds from oriental medicines by intestinal flora, homoorientin [1], a C-glycosylflavonoid was anaerobically incubated with a human intestinal bacterial mixture. Homoorientin [1] was transformed to 6-C-glucosyleriodictyol [2], [U]-eriodictyol [3], luteolin [4], 3,4-dihydroxyphenylpropionic acid [5], and phloroglucinol [6]. A novel cleavage of the C-glycosyl bond was discovered for the first time by using intestinal bacteria.This publication has 2 references indexed in Scilit:
- Studies on the Constituents of Swertia japonica. II. Isolation. and Structure of New Flavonoid, Swertiajaponin.CHEMICAL & PHARMACEUTICAL BULLETIN, 1967
- METABOLIC FATE OF HESPERIDIN, ERIODICTYOL, HOMOERIODICTYOL, AND DIOSMINJournal of Biological Chemistry, 1958