Gliomyosarcoma of the Cerebrum: Report of a Unique Case

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Abstract
A case of an intracerebral fibrosarcoma arising from vascular hyperplasia within a glioma is presented. A unique feature was the presence of further specialized differentiation of the sarcomatous elements in the form of rhabdomyosarcoma. Previous examples of other myosarcomatous neoplasms of the central nervous system are enumerated. Most of these have been of apparent teratoid origin but a few pure rhabdomyosarcomas have been recorded. The acceptance of a mesodermal origin of the leptomeninges and their intracerebral perivascular extensions furnishes a histogenetic basis for the development of meningeal and intracerebral fibrosarcomas. The presence of more specialized nonteratoid mesodermal derivatives within such neoplasms is a logical corollary, but is a rare occurrence.

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