IGA CONTAINING CIRCULATING IMMUNE-COMPLEXES AND IGA ANTI-SINGLE STRANDED DNA ANTIBODIES IN PATIENTS WITH OBSTRUCTIVE-JAUNDICE

  • 1 January 1985
    • journal article
    • research article
    • Vol. 59  (2) , 435-441
Abstract
Elevated levels of IgA containing circulating immune complexes (IgA-CIC) and IgG containing (IgG-) CIC were detected in patients with obstructive jaundice due to biliary tract stones and/or tumor of biliary tract or pancreas. Levels of serum IgA were also elevated, and correlated with the levels of IgA-CIC. The levels of IgA and IgG anti-single stranded (ss)DNA were elevated, and there was a significant correlation between the levels of IgA-CIC and IgA anti-ssDNA antibodies. The cause of IgA-CIC increase in patients with obstructive jaundice might be due not only to simple obstruction of biliary tract but also to other factors such as tissue destruction.