BINDING ADJUVANT-ACTIVE MYCOBACTERIAL PEPTIDOGLYCOLIPIDS AND GLYCOPEPTIDES TOFO MAMMALIAN MEMBRANES AND THEIR EFFECT ON ARTIFICIAL LIPID BILAYERS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 34  (1) , 57-67
Abstract
The nature of the binding of adjuvant-active amphiphilic mycobacterial [Mycobacterium tuberculosis] peptidoglycolipids and glycopeptides to mammalian [e.g., sheep, horse and rabbit] plasma membranes was investigated together with their effect on the stability of artificial lipid bilayers. The importance of these interactions between mycobacterial components and membranes is discussed in relation to immunopotentiation, mitogenicity and tuberculous infection.

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