Triton X-100 Enhances Ion-Pair-Driven Molecular Recognition in Aqueous Media. Further Work on a Chemosensor for Inositol Trisphosphate
- 21 November 2003
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 68 (26) , 10156-10157
- https://doi.org/10.1021/jo030263m
Abstract
Molecular recognition in water based on ion-pairing is hampered by competition from the solvent. We have reported that synthetic receptor 1 recognizes inositol trisphosphate (IP3) with a binding constant of 108 M-1 in methanol. In this paper, instead of working in methanol, we report that the surfactant Triton-X 100 also yields a large absorbance or fluorescence change and a binding constant on the order of 106 M-1.Keywords
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