Uracil derivatives. III. Syntheses and growth-inhibitory activity against L-1210 cells of 5,6-disubstituted uracils.
- 1 January 1982
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 30 (1) , 91-96
- https://doi.org/10.1248/cpb.30.91
Abstract
5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.Keywords
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