Unterschiedliche biologische Aktivität des Hühnerinsulins an der Maus in vivo und in vitro / The Different Biological Activity of Chicken Insulin in Mice Applied in Vivo and in Vitro
Open Access
- 1 November 1969
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 24 (11) , 1424-1428
- https://doi.org/10.1515/znb-1969-1113
Abstract
Chicken insulin was tested in mice in vivo and in vitro. The biological activity was compared to bovine insulin (=100%) as follows: 1. In vitro: Fat pad test 375%; 14C incorporation into the lipids of fat pads 369%: hemidiaphragm insulin assay 373 percent. 2. Localized intraperitoneal action in vivo: 14C incorporation into the fat pads 195%: U-14C-glucose incorporation into glycogen of hemidiaphragm 215 per cent. 3. Mouse convulsion test: The activity was slightly increased.Keywords
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