The Pathogenesis of Ocular Lesions of Infectious Canine Hepatitis: II. Experimental Ocular Hypersensitivity Produced by the Virus
Open Access
- 1 July 1965
- journal article
- research article
- Published by SAGE Publications in Pathologia veterinaria
- Vol. 2 (4) , 344-359
- https://doi.org/10.1177/030098586500200403
Abstract
The pathogenesis of the ocular lesions that occur during convalescence from infectious canine hepatitis was studied in susceptible dogs by passive sensitization, reverse-passive sensitization, and by intraocular inoculation with virus-antibody precipitate suspensions. By these methods it was demonstrated that iridocyclitis and corneal opacification could be produced. These lesions resembled those that occur naturally in this disease. It was concluded that the natural ocular lesions that follow infectious canine hepatitis are a consequence of Arthus-type hypersensitivity reactions.This publication has 3 references indexed in Scilit:
- THE IN VITRO PRODUCTION OF ANTIBODY BY DELAYED PHASE CORNEAL LIMBAL LYMPHOID FOCIThe Journal of Experimental Medicine, 1963
- CONDITIONS INFLUENCING VIRUS-NEUTRALIZATION TESTS FOR INFECTIOUS CANINE HEPATITIS ANTIBODY1963
- Immediate Hypersensitivity Reactions in the Cornea of the Guinea PigThe Journal of Immunology, 1962