Ly phenotype of cytotoxic T cells for syngeneic tumor.
Open Access
- 1 October 1976
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 144 (4) , 1116-1120
- https://doi.org/10.1084/jem.144.4.1116
Abstract
Present and previous findings may be summarized as follows. The phenotype of mouse C57BL/6 (B6) cytotoxic cells for allogeneic target cells is Thy-1+, Ly-1-, Ly-2/3+, MSLA+ and Ig-. The phenotype of B6 cytotoxic cells for syngeneic tumor cells is Thy-+, Ly-1+, Ly-2/3+, MSLA+ and Ig-. Differences in Ly phenotype appear to be exhibited by cytotoxic T [thymus-derived] cells as opposed to helper T cells, and within subcategories of cytotoxic T cells.This publication has 5 references indexed in Scilit:
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- Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.The Journal of Experimental Medicine, 1975
- Cytotoxic Reactions of Murine Lymphoid Cells Studied With a Tritiated Proline Microcytotoxicity Test2JNCI Journal of the National Cancer Institute, 1975
- Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells.The Journal of Experimental Medicine, 1975
- Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouseNature, 1975