Plasma immunoglobulin concentrations in an African (Gambian) community in relation to season, malaria and other infections and pregnancy.

  • 1 July 1970
    • journal article
    • Vol. 7  (1) , 51-74
Abstract
IgG, IgA, IgM and IgD concentrations in plasma were measured at three surveys of a rural Gambian community made over 13 months. 3523 samples were analysed. The pattern of change with age of mean levels of each immunoglobulin class was similar at each survey, although IgM levels were highest in the survey made at the end of the wet season. Immunoglobulin levels in the same individual were found to be relatively stable in adults over the study period. Only minor correlations were found between the levels of different immunoglobulin classes in plasma from the same individual.