OBSERVATIONS ON A CASE OF INTERMITTENT POSTURAL HYPOTENSION

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Abstract
In this case of orthostatic hypotension associated with tabes dorsalis, the hypotensive syndrome occurred intermittently. When the hypotensive syndrome was absent, the blood pressure was maintained at hypertensive levels. When the hypotensive syndrome was present, it could be abolished and the blood pressure raised to hypertensive levels by the effect of muscular ischemia, CO2 and other procedures. The phenomena observed could be explained only by postulating a defect of reflex arteriolar constriction, despite the fact that evidence of a reduction of venous return flow to the heart accompanied the fall of blood pressure which occurred on standing. It was noteworthy that the extreme fluctuations of blood pressure occurred without syncope or significant change in the electrocardiogram or heart size.

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