A Memory Assessment Technique for Use in Geriatric Psychopharmacology: Drug Efficacy Trial with Naftidrofuryl

Abstract
An automated test of paced stimulus material (Sperlings Perceptual Trace, SPT) was compared with several other standard memory scales. Sixty patients with mild senile organic brain syndrome were divided into 2 groups of 30; 1 group was treated for 90 days with 300 mg daily of naftidrofuryl (Praxilene) and the other group received placebo. The patients were tested before treatment and at 30, 60 and 90 days after the beginning of treatment. The SPT indirectly assessed short-term memory, was resistant to practice effects and was drug-sensitive. The SPT might become the test of choice in the indirect assessment of short-term memory in the elderly.

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