Histidine decarboxylase-mediated histamine synthesis in glomeruli from rat kidneys
- 1 May 1976
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 230 (5) , 1349-1353
- https://doi.org/10.1152/ajplegacy.1976.230.5.1349
Abstract
Enzymatic histamine synthesis by renal glomeruli of the rat has been examined. Assays of the partially purified enzyme demonstrated a pH optimum of 6.2, a Michaelis-Menten constant of 2.4 X 10(-4) histidine, and lack of potentiation by benzene. These data thus indicate that renal glomeruli contain the histidine-specific histidine decarboxylase.Keywords
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