H2 Antagonist-induced thrombocytopenia: is this a real phenomenon?
- 15 January 2002
- journal article
- review article
- Published by Springer Nature in Intensive Care Medicine
- Vol. 28 (4) , 459-465
- https://doi.org/10.1007/s00134-002-1233-6
Abstract
Critically ill patients routinely receive H2 antagonists for stress ulcer prophylaxis while at risk for gastrointestinal bleeding. In these patients it is often difficult to assess accurately the cause of adverse effects such as thrombocytopenia. We evaluate the literature to better define thrombocytopenia related to H2 antagonist administration and discuss mechanism, potential as a risk factor and case reports describing the severity and duration of thrombocytopenia.Keywords
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