Effects of Calcium Deficiency and Pyridoxin Deficiency on Thymic Atrophy (Accidental Involution)

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Abstract
In [male] albino rats (8 wks. of age) exposed to a number of adverse dietary conditions, an approx. linear relationship was found between the amt. of body wt. deficit and the thymus wt. deficit. There were 2 exceptions from this apparent rule: (1) in pyridoxin de-ficiency, the amt. of thymus wt. deficit was much greater than expected from the obtained body wt. deficit; (2) in Ca de-ficiency an opposite effect was observed. Here the thymi of undersized animals were of the same wt. as those of younger, normal animals of the same body wt.