Effect of Development and Aging on the Response of Canine Lymphocytes to Phytohemagglutinin
- 1 October 1974
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 10 (4) , 695-699
- https://doi.org/10.1128/iai.10.4.695-699.1974
Abstract
The stage of development and age were found to effect the responsiveness of dog T-lymphocytes to phytohemagglutinin. T-lymphocytes from beagles 0 to 4 weeks of age showed significantly less response to phytohemagglutinin (P < 0.001) than T-lymphocytes from these same dogs at 6 to 12 weeks of age. Peak response to phytohemagglutinin occurred between 6 weeks to 6 months of age, after which there was a significant correlation (P < 0.02) between increase in age and decrease in phytohemagglutinin responsiveness.Keywords
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