Fluorocarbon-Polyol Artificial Blood Substitutes

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Abstract
THERE are many reasons for seeking an artificial whole-blood substitute that can replace both plasma proteins and cells. Perfusion of organs for metabolic studies or transplant purposes would alone make the development of such a product worthwhile. Complete perfusion of living animals with an artificial preparation would afford the opportunity to carry out many investigations not possible when normal blood is present. The eventual formulation of a safe, practical whole-blood substitute would be of possible value in cases in which normal blood might otherwise be used. Interest in complete replacement of the blood of living animals1 rather than the usual . . .