Neuronal antinuclear antibodies in a patient with Lambert‐Eaton myasthenic syndrome and small‐cell lung carcinoma
- 1 February 1989
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 39 (2) , 249
- https://doi.org/10.1212/wnl.39.2.249
Abstract
A patient with small-cell lung carcinoma and the Lambert-Eaton myasthenic syndrome had circulating neuronal antinuclear antibodies. Serum stained the nuclei of all neurons in sections of human brain and identified a closely spaced group of 33-39 kDa proteins in immunoblots of human neuronal nuclei. These autoantibodies are indistinguishable from those recently identified in patients with paraneoplastic subacute sensory neuronopathy.This publication has 5 references indexed in Scilit:
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