EBER2 RNA-induced transcriptome changes identify cellular processes likely targeted during Epstein Barr Virus infection
Open Access
- 1 January 2008
- journal article
- Published by Springer Nature in BMC Research Notes
- Vol. 1 (1) , 100
- https://doi.org/10.1186/1756-0500-1-100
Abstract
Little is known about the physiological role of the EBER1 and 2 nuclear RNAs during Epstein Barr viral infection. The EBERs are transcribed by cellular RNA Polymerase III and their strong expression results in 106 to 107 copies per EBV infected cell, making them reliable diagnostic markers for the presence of EBV. Although the functions of most of the proteins targeted by EBER RNAs have been studied, the role of EBERs themselves still remains elusive.Keywords
This publication has 25 references indexed in Scilit:
- The role of Epstein–Barr virus in cancerExpert Opinion on Biological Therapy, 2006
- Multiple domains of EBER 1, an Epstein-Barr virus noncoding RNA, recruit human ribosomal protein L22RNA, 2006
- Infection with Epstein-Barr virus and cancer: an epidemiological review.2005
- Epstein–Barr virus: 40 years onNature Reviews Cancer, 2004
- Efficient transcription of the EBER2 gene depends on the structural integrity of the RNARNA, 2003
- Epstein–Barr virus‐associated carcinomas: facts and fictionThe Journal of Pathology, 2003
- Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues.1992
- Viral latency and transformation: The strategy of Epstein-Barr virusCell, 1989
- Two small RNAs encoded by Epstein-Barr virus can functionally substitute for the virus-associated RNAs in the lytic growth of adenovirus 5.Proceedings of the National Academy of Sciences, 1983
- Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus.Proceedings of the National Academy of Sciences, 1981