The concentration of coenzyme-like substance in blood following the administration of nicotinic acid to normal individuals and pellagrins
- 1 December 1938
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 32 (12) , 2075-2083
- https://doi.org/10.1042/bj0322075
Abstract
The bio-assay of blood V-factor was accomplished by means of Haemophilus parainfluenzae; V-factor represented the di- and tri-phosphopyridine nucleotide coenzymes, and possibly, closely related substances which were unknown. Nicotinic acid (or amide) did not give the test. V-factor was confined to the corpuscles. About 20 mg. nicotinic acid per kg. taken in 1-10 days increased V by 35-75% in 2-10 days in normal individuals and pellagrins. The rapid rise in V was followed by a fairly rapid fall to the original level.This publication has 5 references indexed in Scilit:
- TREATMENT OF BLACKTONGUE WITH COZYMASEScience, 1938
- Experiments with pigs on a pellagra-producing diet. IIBiochemical Journal, 1938
- Nicotinic Acid and Vitamin B 2Science, 1937
- The nutrition of Staphylococcus aureus; nicotinic acid and vitamin B1Biochemical Journal, 1937