Floxacillin-Induced Cholestatic Hepatitis With Evidence of Lymphocyte Sensitization
- 1 May 1987
- journal article
- case report
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 147 (5) , 987-989
- https://doi.org/10.1001/archinte.1987.00370050179030
Abstract
• A severe and prolonged form of biopsy-proved cholestatic hepatitis occurred in a 45-year-old man who had received floxacillin for two weeks preceding the episode of drug-related cholestatic injury. Immunologic tests revealed evidence of in vitro sensitization to the drug as well as to the serum of a normal subject collected after ingestion of floxacillin. Floxacillin should be added to the list of drugs causing cholestatic hepatitis, most likely by an immunologic mechanism. (Arch Intern Med 1987;147:987-989)Keywords
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