Abstract
A comparison of the A1-test and the chamber test was made by performing epicutaneous tests simultaneously with both methods on symmetrical sites of the upper back. Irritant reactions were provoked with 1.5% benzalkonium chloride on 90 patients. Allergic reactions were studied with 10 allergens on 510 patients; 243 gave positive reactions to 1 or more of the test substances. Results obtained by these methods were about the same when the A1-test was fixed with nonporous occlusive plaster (Leukoplast). By fixing the A1-test units like the chambers with a porous tape (Scanpor), the chamber test produced more irritant and allergic reactions than the A1-test.