First Report of Capsule Replacement among Electrophoretic Type 37 Neisseria meningitidis Strains in Italy
Open Access
- 1 December 2003
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 41 (12) , 5783-5786
- https://doi.org/10.1128/jcm.41.12.5783-5786.2003
Abstract
This report describes the C-to-B capsular switching in four Neisseria meningitidis strains belonging to the electrophoretic type 37 (ET-37) complex. In particular, one strain belonged to the new sequence type 1860, which was first detected in the year 2000 in Italy and is now frequently isolated. The presence of switched serogroup B strains deserves special attention if they prove as able to spread as their serogroup C progenitors belonging to the hypervirulent ET-37 complex.Keywords
This publication has 16 references indexed in Scilit:
- Comparison of PorA VR types and porA promoter sequence from Neisseria meningitidis B isolated from non-immunised children and vaccine failures immunised with a serogroup B outer membrane protein vaccineVaccine, 2003
- Serotype Distribution, Antibiotic Susceptibility, and Genetic Relatedness ofNeisseria meningitidisStrains Recently Isolated in ItalyClinical Infectious Diseases, 2003
- The epidemic wave of meningococcal disease in Spain in 1996–1997: probably a consequence of strain displacementJournal of Medical Microbiology, 2002
- Capsule Switching among C:2b:P1.2,5 Meningococcal Epidemic Strains after Mass Immunization Campaign, SpainEmerging Infectious Diseases, 2002
- Positive effect of meningococcal C vaccination on serogroup replacement in Neisseria meningitidisThe Lancet, 2002
- Genetic Isolation of Meningococci of the Electrophoretic Type 37 ComplexJournal of Bacteriology, 2001
- Genosubtyping by sequencing group A, B and C meningococci; a tool for epidemiological studies of epidemics, clusters and sporadic casesNoteAPMIS, 2000
- Capsule switching of Neisseria meningitidisProceedings of the National Academy of Sciences, 1997
- Typing of sequential bacterial isolates by pulsed-field gel electrophoresisDiagnostic Microbiology and Infectious Disease, 1995
- Transformation-mediated exchange of virulence determinants by co-cultivation of pathogenic NeisseriaeFEMS Microbiology Letters, 1992