Site-directed Mutagenesis of Glutamate 166 in Two β-Lactamases
Open Access
- 1 February 1997
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 272 (9) , 5438-5444
- https://doi.org/10.1074/jbc.272.9.5438
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Structural Basis of Extended Spectrum TEM β-LactamasesPublished by Elsevier ,1996
- TEM1 β-lactamase structure solved by molecular replacement and refined structure of the S235A mutantActa Crystallographica Section D-Biological Crystallography, 1995
- TEM β-Lactamase Mutants Hydrolysing Third-generation Cephalosporins: A Kinetic and Molecular Modelling AnalysisJournal of Molecular Biology, 1994
- Evolution of antibiotic resistance: several different amino acid substitutions in an active site loop alter the substrate profile of β‐lactamaseMolecular Microbiology, 1994
- A catalytically-impaired class A β-lactamase: 2 Å crystal structure and kinetics of the Bacillus licheniformis E166A mutantProtein Engineering, Design and Selection, 1993
- Site-directed mutagenesis of .beta.-lactamase leading to accumulation of a catalytic intermediateBiochemistry, 1991
- Structural basis for the inactivation of the P54 mutant of .beta.-lactamase from Staphylococcus aureus PC1Biochemistry, 1991
- Refined crystal structure of β-lactamase from Staphylococcus aureus PC1 at 2.0 Å resolutionJournal of Molecular Biology, 1991
- Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular modelJournal of the American Chemical Society, 1985
- Interaction between β‐Lactam Antibiotics and Exocellular dd‐Carboxypeptidase‐Transpeptidase of Streptomyces R61European Journal of Biochemistry, 1974