Salt-induced Z-A-Z transition sequence in the mixed ribo-deoxyribo copolymer poly(rG-dC) X poly(rG-dC).
- 1 December 1984
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 81 (23) , 7284-7287
- https://doi.org/10.1073/pnas.81.23.7284
Abstract
The left-handed helical conformation of various polynucleotides has been seen in solution at higher salt concentration than has the right-handed helical conformation of the corresponding polymer. However, studies of conformational transitions in the mixed polymer poly(rG-dC).cntdot.poly(rG-dC) showed that this polynucleotide appears to exist in a Z conformation under low-salt conditions, converts to an A helix at intermediate salt, and reverts to a left-handed helix at high-salt concentration.This publication has 21 references indexed in Scilit:
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