A NEW SYNTHETIC METHOD FOR β-SUBSTITUTED Δα,β-BUTENOLIDES
- 5 October 1974
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 3 (10) , 1237-1240
- https://doi.org/10.1246/cl.1974.1237
Abstract
α-Phenylsulfinyllactones 2 underwent the Pummerer rearrangement and subsequent elimination of acetic acid by treating with hot acetic anhydride to give α-phenylthiobutenolides 4. Conjugate addition reaction of 4 with organocopper reagents or malonic ester followed by oxidation to sulfoxides and pyrolysis afforded β-monosubstituted or β,γ-disubstituted butenolides 6 in moderate overall yields.This publication has 8 references indexed in Scilit:
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