Diabetic Lipemia with Maturity-Onset Diabetes of the Young.
- 1 January 1997
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 36 (8) , 571-574
- https://doi.org/10.2169/internalmedicine.36.571
Abstract
A 19-year-old woman with diabetic lipemia and maturity-onset diabetes of the young (MODY) is reported. Though her insulin secretory activity was preserved, she fell into mild diabetic ketoacidosis (DKA) and showed type V hyperlipidemia. Post-heparin plasma activity of lipoprotein lipase (LPL) was decreased even 10 days after initiating insulin injection but not deficient. The abnormalities in lipid metabolism were improved by long-term insulin treatment. Though the contribution of the genetic background to the lipid abnormalities is not clear, the characteristics of MODY in this patient including insulin secretory capacity under stress conditions such as DKA might play a role in the development of diabetic lipemia.Keywords
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