The presence of a calcium‐sensitive p26‐containing complex in bovine retina rod cells
- 6 December 1993
- journal article
- Published by Wiley in FEBS Letters
- Vol. 335 (2) , 277-279
- https://doi.org/10.1016/0014-5793(93)80746-h
Abstract
A protein with apparent Mr, 26 kDa (p26 [(1991) Biokhnya 56, 225-228] or recoverin [(1991) Science 251, 915-918]) was suggested to activate GC in a calcium dependent manner in bovine retina rod cells [(1991) Science 251, 915-918; (1991) EMBO J, 10, 793-798]. However, according to our present data homogeneous p26 preparations do not activate the enzyme. At the same time we have revealed a complex of p26 with an unidentified protein, presumably RK, in bovine ROS. Calcium favours formation of the complex whereas EGTA addition (which corresponds to a low free Ca2+ concentration) leads to its dissociationKeywords
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