Abstract
N''-Beta-phenethylformamidinyliminourea (DBI), a new synthetic substance administered parenterally and orally causes hypo-glycemia in guinea pigs, rats, rabbits, cats and Rhesus monkeys. Its activity is evident in the young patient with severe labile diabetes mellitus as well as in those with moderately severe and mild diabetes, without manifestations of toxicity. At present there is a limitation of dosage due to nausea and occasional vomiting.

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