Intermittent Acute Porphyria Treated with Chlorpromazine

Publisher Website
Google Scholar
Abstract
INTERMITTENT acute porphyria reflects a fundamental disturbance of porphyrin metabolism at the cellular level, and its recognition is a challenging clinical event.In the past, treatment of this curious condition has been singularly ineffective and most frustrating. Thus, one recalls early but inconstant success with a variety of agents, including liver extract, vitamins, antihistamines, ganglionic-blocking agents, ACTH, corticosteroids and innumerable others aimed at control of one or more distressing symptoms.The purpose of this communication is to call attention to the striking amelioration of pain and nervousness that has been observed during chlorpromazine therapy of 4 porphyric patients during the . . .