Do some patients with fragile X syndrome have precocious puberty?
- 1 December 1988
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 31 (4) , 779-781
- https://doi.org/10.1002/ajmg.1320310408
Abstract
We report on an 81½‐year‐old white girl with fra (X) syndrome; she had mental deficiency, hyperactivity, speech disturbances, slightly prominent ears, mild joint laxity and 20% fra (X) expression. Additional findings include idiopathic precocious puberty and a right ovarian cyst. Ovarian cysts have been reported previously in heterozygous females, but to our knowledge idiopathic precocious puberty is a new finding in this syndrome. Whether precocious puberty is a coincidental finding in this patient or a previously unreported manifestation of the fra (X) syndrome is not clear.Keywords
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